SCHEMBL974629

SCHEMBL974629

CCCCn1c2cc[c]cc2c2c[c]ccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 5/20 0.44
RORA P35398 5/20 0.44
RORC P51449 5/20 0.44
RORB Q92753 5/20 0.44
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 4/20 0.40
KDM4E B2RXH2 2/20 0.37
HPGD P15428 2/20 0.37
LMNA P02545 1/20 0.37
NPC1 O15118 2/20 0.37
ALPL P05186 1/20 0.36
ALPG P10696 1/20 0.36
TSHR P16473 2/20 0.36
TLR8 Q9NR97 1/20 0.36
PSEN1 P49768 2/20 0.35
PSEN2 P49810 2/20 0.35
APH1B Q8WW43 2/20 0.35
NCSTN Q92542 2/20 0.35
APH1A Q96BI3 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11142970 0.92 PGR (0.56) PGRRORARORCRORBL3MBTL1
SCHEMBL973904 0.89 HPGD (0.40) PGRRORARORCRORBTDP1
SCHEMBL14976913 0.87 PGR (0.51) PGRRORARORCRORBKDM4E
SCHEMBL8697242 0.86 PSEN1 (0.52) PGRRORARORCRORBKDM4E
SCHEMBL28517524 0.86 PSEN1 (0.52) PGRRORARORCRORBKDM4E
SCHEMBL975310 0.85 PGR (0.44) PGRRORARORCRORBL3MBTL1
SCHEMBL975523 0.80 ALDH1A1 (0.44) L3MBTL1TDP1ALDH1A1KDM4EHPGD
SCHEMBL6420678 0.79 PSEN1 (0.43) PGRRORARORCRORBTLR8
SCHEMBL6420677 0.79 PSEN1 (0.43) PGRRORARORCRORBTLR8
SCHEMBL6423058 0.79 PSEN1 (0.43) PGRRORARORCRORBTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8475937-B2 Silicone composition and organic light-emitting diode DOW CORNING CORPORATION (US) 2013-07-02 US disclosed
EP-2262861-B1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING (US) 2012-09-19 EP disclosed
US-20110017986-A1 Silicone Composition and Organic Light-Emitting Diode DOW CORNING CORPORATION 2011-01-27 US disclosed
EP-2262861-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE Dow Corning Corporation (US) 2010-12-22 EP disclosed
WO-2009120434-A1 SILICONE COMPOSITION AND ORGANIC LIGHT-EMITTING DIODE DOW CORNING CORPORATION (US) 2009-10-01 WO disclosed