Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CCL2 | P13500 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89374 | 1.00 | POLB (0.49) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL8694188 | 1.00 | POLB (0.49) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL28304038 | 0.98 | POLB (0.47) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL6700611 | 0.85 | POLB (0.39) | POLBALDH1A1KDM4ERETKMT2A | |
| SCHEMBL30931450 | 0.84 | POLB (0.38) | POLBALDH1A1KDM4ERETKMT2A | |
| SCHEMBL17222502 | 0.83 | POLB (0.37) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL459671 | 0.83 | POLB (0.37) | POLBALDH1A1KDM4ERETHPGD | |
| SCHEMBL15664847 | 0.83 | POLB (0.37) | POLBALDH1A1KDM4ERETKMT2A | |
| SCHEMBL28022821 | 0.82 | POLB (0.39) | POLBALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL27926152 | 0.82 | ALDH1A1 (0.38) | POLBALDH1A1KDM4ERETHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5731464-A | AZIDE INTERMEDIATES | CHISSO CORPORATION (JP) | 1998-03-24 | — | — | US | disclosed |