SCHEMBL869742

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL871282	0.90	PDK2 (0.37)	PDK2ORAI1CA1CA2KDM4E
	SCHEMBL870662	0.90	PDK2 (0.39)	PDK2CA1CA2KDM4EMEN1
	SCHEMBL871548	0.89	PDK2 (0.40)	PDK2ORAI1CA1CA2KDM4E
	SCHEMBL10072347	0.88	CA1 (0.35)	PDK2FABP4FABP5CA1CA2
	SCHEMBL876189	0.88	CA1 (0.33)	CA1CA2CXCR5DHODHRARA
	SCHEMBL871382	0.88	PDK2 (0.36)	PDK2ORAI1CA1CA2DHODH
	SCHEMBL21863425	0.88	PDK2 (0.36)	PDK2ORAI1CA1CA2DHODH
	SCHEMBL869975	0.87	ALOX5AP (0.35)	ORAI1CXCR5MEN1ALDH1A1KMT2A
	SCHEMBL870417	0.86	PDK2 (0.34)	PDK2FABP4FABP5ORAI1CA1
	SCHEMBL869976	0.86	KDM4E (0.35)	PDK2ORAI1KDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.