Sugi Predict

Sugi Predict / Compounds / SCHEMBL871382

SCHEMBL871382

SCHEMBL871382

O=C(O)c1ccc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)c2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 4/20 0.36
▸ ORAI1 Q96D31 3/20 0.33
▸ DHODH Q02127 1/20 0.33
▸ TYMS P04818 1/20 0.32
▸ ACLY P53396 2/20 0.32
▸ KCNJ6 P48051 1/20 0.32
▸ KCNJ5 P48544 1/20 0.32
▸ KCNJ3 P48549 1/20 0.32
▸ RECQL P46063 1/20 0.31
▸ HPGD P15428 3/20 0.31
▸ MAPT P10636 3/20 0.31
▸ KDM4E B2RXH2 2/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ HTT P42858 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ HSD17B10 Q99714 2/20 0.31
▸ TP53 P04637 1/20 0.31
▸ TSHR P16473 1/20 0.31
▸ MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21863425 1.00 PDK2 (0.36) PDK2ORAI1DHODHTYMSACLY
SCHEMBL870417 0.94 PDK2 (0.34) PDK2ORAI1DHODHACLYCA1
SCHEMBL1936965 0.94 FABP4 (0.34) PDK2ORAI1DHODHTYMSACLY
SCHEMBL2780339 0.93 ACLY (0.38) PDK2ORAI1DHODHACLYMEN1
SCHEMBL30313890 0.93 ACLY (0.38) PDK2ORAI1DHODHACLYMEN1
SCHEMBL13458407 0.93 PDK2 (0.33) PDK2ORAI1DHODH
SCHEMBL3107680 0.92 PDK2 (0.39) PDK2ORAI1HPGDKMT2A
SCHEMBL871548 0.91 PDK2 (0.40) PDK2ORAI1TYMSHPGDMAPT
SCHEMBL871282 0.90 PDK2 (0.37) PDK2ORAI1TYMSHPGDMAPT
SCHEMBL21863693 0.89 PDK2 (0.39) PDK2ORAI1HPGDCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 — — EP claimed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 — — EP claimed
EP-3300602-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2018-04-04 — — EP claimed
US-20160219872-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION 2016-08-04 — — US claimed
US-9339030-B2 Foamable pesticide compositions and methods of application BASF CORPORATION (US) 2016-05-17 — — US claimed
US-20150105258-A1 Methods For Controlling Pests BASF CORPORATION (US) 2015-04-16 — — US claimed
US-8980294-B2 Methods for controlling pests BASF CORPORATION (US) 2015-03-17 — — US claimed
US-8940662-B2 Methods for controlling pests BASF CORPORATION (US) 2015-01-27 — — US claimed
WO-2014063942-A1 SUBSTITUTED PESTICIDAL PYRAZOLE COMPOUNDS BASF SE (DE) 2014-05-01 — — WO claimed
US-20140017216-A1 PESTICIDAL MIXTURES BAYER CROPSCIENCE LP (US) 2014-01-16 — — US claimed
EP-2575471-A1 PESTICIDAL MIXTURES BASF SE (DE) 2013-04-10 — — EP claimed
US-20130012386-A1 Methods For Controlling Pests BASF CORPORATION (US) 2013-01-10 — — US claimed
EP-2470007-A2 FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION BASF Corporation (US) 2012-07-04 — — EP claimed
WO-2012084670-A1 PESTICIDAL ACTIVE MIXTURES COMPRISING PYRAZOLE COMPOUNDS BASF SE (DE) 2012-06-28 — — WO claimed
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION (US) 2012-06-14 — — US claimed
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-12-23 — — US claimed
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-12-23 — — US claimed
US-20100322990-A1 METHODS FOR CONTROLLING PESTS BASF CORPORATION (US) 2010-12-23 — — US claimed
WO-2010129345-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-11-11 — — WO claimed
WO-2010127019-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-11-04 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE PDK2 1599/4885ORAI1 1911/4885DHODH 1116/4885
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS DDT, PON1, ACHE PDK2 1918/4885ORAI1 880/4885DHODH 718/4885
US-20130012386-A1 Methods For Controlling Pests DDT, ACHE, PON1 PDK2 3253/4885ORAI1 1712/4885DHODH 1877/4885
US-20100322990-A1 METHODS FOR CONTROLLING PESTS DDT, ACHE, PON1 PDK2 3253/4885ORAI1 1712/4885DHODH 1877/4885
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS DDT, ACHE, CHRM2 PDK2 3749/4885ORAI1 610/4885DHODH 2887/4885
US-20150105258-A1 Methods For Controlling Pests DDT, ACHE, PON1 PDK2 3253/4885ORAI1 1712/4885DHODH 1877/4885
US-20160219872-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE PDK2 1599/4885ORAI1 1911/4885DHODH 1116/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.