Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700537 | 0.88 | CYP19A1 (0.47) | CYP19A1CYP2A6CYP26A1MAPT | |
| SCHEMBL8697788 | 0.84 | CYP19A1 (0.60) | CYP19A1CYP2A6CYP26A1MAPT | |
| SCHEMBL8700529 | 0.75 | CYP19A1 (0.73) | CYP19A1TSHRCYP26A1 | |
| SCHEMBL8699998 | 0.75 | CYP26A1 (0.44) | CYP19A1ALDH1A1CYP26A1NPC1RAB9A | |
| SCHEMBL8697486 | 0.74 | CYP19A1 (0.46) | CYP19A1TSHRCYP26A1NPC1RAB9A | |
| SCHEMBL8700053 | 0.74 | CYP19A1 (0.51) | CYP19A1CYP2A6KDM4EALDH1A1PKM | |
| SCHEMBL8696314 | 0.73 | CYP19A1 (0.41) | CYP19A1CYP2A6KDM4EALDH1A1HPGD | |
| SCHEMBL29707706 | 0.71 | CYP19A1 (0.55) | CYP19A1CYP2A6KDM4EALDH1A1TSHR | |
| SCHEMBL28562505 | 0.71 | CYP19A1 (0.55) | CYP19A1CYP2A6KDM4EALDH1A1TSHR | |
| SCHEMBL8702387 | 0.70 | CYP19A1 (0.55) | CYP19A1KDM4EALDH1A1HPGDCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |