Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8702186 | 0.88 | CYP19A1 (0.47) | CYP19A1CYP2A6CYP26A1MAPT | |
| SCHEMBL8697486 | 0.85 | CYP19A1 (0.46) | CYP19A1CYP26A1CYP3A4 | |
| SCHEMBL8697788 | 0.83 | CYP19A1 (0.60) | CYP19A1CYP2A6CYP26A1MAPT | |
| SCHEMBL8700262 | 0.79 | CYP19A1 (0.42) | CYP19A1KCNH2CYP3A4 | |
| SCHEMBL8702245 | 0.75 | CYP19A1 (0.72) | CYP19A1CYP26A1CYP3A4 | |
| SCHEMBL8697118 | 0.74 | CYP19A1 (0.55) | CYP19A1CYP26A1MAOAMAOB | |
| SCHEMBL8697624 | 0.74 | CYP19A1 (0.50) | CYP19A1CYP2A6CYP26A1MAPT | |
| SCHEMBL8699998 | 0.74 | CYP26A1 (0.44) | CYP19A1CYP26A1 | |
| SCHEMBL8696314 | 0.72 | CYP19A1 (0.41) | CYP19A1CYP2A6MAPTKCNH2CYP3A4 | |
| SCHEMBL8700871 | 0.72 | CYP3A4 (0.43) | CYP19A1CYP2A6MAPTKCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998018791-A1 | HETEROCYCLIC FURAN COMPOUNDS, THEIR PREPARATION AND USE AS AROMATASE INHIBITORS | A. MENARINI INDUSTRIE FARMACEUTICHE RIUNITE S.R.L. (IT) | 1998-05-07 | — | — | WO | claimed |