Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 12/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | CTRC | Q99895 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697603 | 0.88 | HTR6 (0.45) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8697954 | 0.82 | F2 (0.39) | HTR6F2PRSS2F10CTRC | |
| Hydrochloric Acid SCHEMBL8696200 | 0.81 | F2 (0.41) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8697958 | 0.81 | F2 (0.46) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8694486 | 0.81 | F2 (0.46) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8696210 | 0.80 | STS (0.45) | HTR6F2PRSS2F10LMNA | |
| SCHEMBL8697599 | 0.80 | F2 (0.58) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8698423 | 0.80 | F2 (0.39) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8695388 | 0.79 | F2 (0.44) | HTR6F2PRSS2F10CTRC | |
| SCHEMBL8696257 | 0.79 | F2 (0.44) | HTR6F2PRSS2F10CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | claimed |
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |