Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 9/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697495 | 0.79 | LMNA (0.52) | FPR2CACNA1GCACNA1HLMNACCR5 | |
| SCHEMBL22623697 | 0.77 | LMNA (0.50) | FPR2LMNACCR5MEN1RAB9A | |
| SCHEMBL3990757 | 0.74 | LMNA (0.51) | FPR2LMNA | |
| SCHEMBL8538799 | 0.73 | PDE4B (0.53) | POLBNPC1TDP1PDE4BLMNA | |
| SCHEMBL21581188 | 0.73 | HDAC6 (0.62) | POLBLMNAKMT2A | |
| SCHEMBL16407625 | 0.73 | BRD4 (0.59) | FPR2LMNA | |
| SCHEMBL16591625 | 0.72 | POLB (0.69) | POLBNPC1TDP1L3MBTL1MEN1 | |
| SCHEMBL14028152 | 0.72 | POLB (0.73) | POLBNPC1TDP1LMNAL3MBTL1 | |
| SCHEMBL6289171 | 0.72 | POLB (0.77) | POLBNPC1TDP1L3MBTL1MEN1 | |
| SCHEMBL2603249 | 0.71 | POLB (0.68) | POLBNPC1TDP1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |