Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13687264 | 0.86 | CCR5 (0.68) | LMNATSHRCACNA1GCACNA1HCYP2D6 | |
| SCHEMBL14187574 | 0.82 | CCR5 (0.76) | CYP2D6CCR5DRD2DRD4DRD3 | |
| SCHEMBL22623697 | 0.80 | LMNA (0.50) | LMNATSHRRECQLCCR5MAPT | |
| SCHEMBL8697885 | 0.79 | FPR2 (0.53) | LMNARECQLCACNA1GCACNA1HCCR5 | |
| SCHEMBL3289777 | 0.79 | MCHR1 (0.50) | CYP2D6CCR5FPR2CCR3MEN1 | |
| SCHEMBL3291013 | 0.79 | FPR2 (0.46) | LMNATSHRCACNA1GCACNA1HCYP2D6 | |
| SCHEMBL3293907 | 0.78 | CCR3 (0.65) | DRD2DRD3GRM2SIGMAR1FPR2 | |
| SCHEMBL4153717 | 0.76 | LMNA (0.52) | LMNATSHRCYP2D6DRD2DRD4 | |
| SCHEMBL4146653 | 0.75 | GRM2 (0.67) | LMNADRD2DRD4DRD3GRM2 | |
| SCHEMBL3291520 | 0.74 | TP53 (0.49) | LMNAMAPTOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |