SCHEMBL8697932

SCHEMBL8697932

C#CCn1c(C(F)(F)F)nc2cc(F)c(N)cc21

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP3A4 P08684 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8694354 0.78 CYP2C9 (0.42) CYP2C9CYP2C19CYP3A4MEN1KMT2A
SCHEMBL28079891 0.73 CYP2C9 (0.55) CYP2C9CYP2C19CYP3A4MEN1KMT2A
SCHEMBL8698250 0.72
SCHEMBL9874621 0.64 CD74 (0.35) KMT2A
SCHEMBL24463113 0.60 LMNA (0.40) CYP2C9CYP2C19MEN1KMT2ACYP1A2
SCHEMBL13358850 0.60 KDM4E (0.61) MEN1KMT2ACYP1A2CYP2D6
SCHEMBL5015544 0.56 CYP2C9 (0.46) CYP2C9CYP2C19CYP3A4MEN1KMT2A
SCHEMBL11810730 0.56 KDM4E (0.52) KMT2ACYP1A2
SCHEMBL23415054 0.56 ADORA3 (0.32)
SCHEMBL31600189 0.55 NPC1 (0.40) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998018768-A1 HERBICIDAL 3-(BICYCLIC NITROGEN-CONTAINING HETEROCYCLE)-SUBSTITUTED-1-METHYL-6-TRIFLUOROMETHYLURACILS FMC CORPORATION (US) 1998-05-07 WO disclosed
US-5661108-A CONTROLLING PLANT GROWTH FMC CORPORATION (US) 1997-08-26 US disclosed