Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340061 | 0.92 | NUDT1 (0.46) | CYP2C9CYP2C19CYP3A4KMT2AHTR3E | |
| SCHEMBL5015559 | 0.85 | KMT2A (0.53) | CYP2C9CYP2C19KMT2AKDM4EHTT | |
| SCHEMBL12968163 | 0.80 | CYP2C9 (0.59) | CYP2C9CYP2C19CYP3A4KMT2AKDM4E | |
| SCHEMBL8694354 | 0.78 | CYP2C9 (0.42) | CYP2C9CYP2C19CYP3A4KMT2AKDM4E | |
| SCHEMBL5015603 | 0.77 | CNR2 (0.47) | CYP2C9CYP2C19CYP3A4KMT2AHTT | |
| SCHEMBL8337211 | 0.75 | CNR2 (0.43) | CYP2C9CYP2C19CYP3A4KMT2AKDM4E | |
| SCHEMBL8336401 | 0.74 | PKM (0.47) | — | |
| SCHEMBL14331825 | 0.72 | HDAC1 (0.53) | CYP2C9CYP2C19CYP3A4TBXA2R | |
| SCHEMBL8341001 | 0.71 | MEN1 (0.36) | CYP2C9CYP2C19CYP3A4KMT2AKDM4E | |
| SCHEMBL29006852 | 0.71 | TBXA2R (0.45) | CYP2C19CYP3A4KMT2AHTR3AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220073536-A1 | METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES WITH 2,4-PYRIMIDINEDIAMINE COMPOUNDS | RIGEL PHARMACEUTICALS, INC. (US) | 2022-03-10 | — | — | US | disclosed |
| US-7456293-B2 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SK HOLDING CO., LTD (KR) | 2008-11-25 | — | — | US | disclosed |
| EP-1869004-A1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS, THEIR PREPARATION AND USE | SK Holdings Co., Ltd. (KR) | 2007-12-26 | — | — | EP | disclosed |
| US-20060281802-A1 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2006-12-14 | — | — | US | disclosed |
| WO-2006104349-A1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES FOR THE TREATMENT OF DIABETES AND LIPID DISORDERS, THEIR PREPARATION AND USE | SK HOLDINGS CO., LTD. (KR) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220073536-A1 | METHODS OF TREATING OR PREVENTING AUTOIMMUNE DISEASES WITH 2,4-PYRIMIDINEDIAMINE COMPOUNDS | SSB, TPMT, ADAR | CYP2C9 4110/4885CYP2C19 4411/4885CYP3A4 4101/4885 |
| US-20060281802-A1 | Substituted carboxylic acid derivatives for the treatment of diabetes and lipid disorders, their preparation and use | SLC5A1, CPT1A, GPR119 | CYP2C9 259/4885CYP2C19 261/4885CYP3A4 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.