Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 6/20 | 0.44 |
| ▸ | CDK2 | P24941 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698026 | 0.87 | CCNE1 (0.43) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL6984805 | 0.81 | ALDH1A1 (0.42) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL8698485 | 0.70 | MAPT (0.46) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL6982096 | 0.70 | MAPT (0.46) | CCNE1CDK2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8699214 | 0.69 | MAPT (0.45) | CCNE1CDK2MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL8699219 | 0.69 | MAPT (0.45) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL8696015 | 0.69 | ALDH1A1 (0.42) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL6805625 | 0.68 | PARP1 (0.64) | PARP1 | |
| SCHEMBL8595591 | 0.68 | CTSV (0.46) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL6805633 | 0.67 | PARP1 (0.44) | CCNE1CDK2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780437-A | ADMINISTERING TO TREAT SEX-HORMONE RELATED DISORDERS | MERCK & CO., INC. (US) | 1998-07-14 | — | — | US | disclosed |