Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038835 | 0.91 | L3MBTL1 (0.36) | ELANERAB9APLCG1L3MBTL1ALDH1A1 | |
| SCHEMBL8038854 | 0.87 | RAB9A (0.38) | ELANERAB9APLCG1L3MBTL1ALDH1A1 | |
| SCHEMBL8040724 | 0.86 | PLCG1 (0.38) | ELANERAB9APLCG1SMN1; SMN2CCR5 | |
| SCHEMBL8040733 | 0.83 | ELANE (0.40) | ELANERAB9APLCG1L3MBTL1 | |
| SCHEMBL8046000 | 0.83 | ELANE (0.38) | ELANERAB9APLCG1L3MBTL1SMN1; SMN2 | |
| SCHEMBL8042511 | 0.78 | DPP8 (0.36) | RAB9APLCG1L3MBTL1NPC1SMN1; SMN2 | |
| SCHEMBL19775159 | 0.76 | PLCG1 (0.42) | ELANERAB9APLCG1L3MBTL1ALDH1A1 | |
| SCHEMBL9664427 | 0.76 | PLCG1 (0.42) | ELANERAB9APLCG1L3MBTL1 | |
| SCHEMBL9640039 | 0.76 | PLCG1 (0.42) | ELANERAB9APLCG1L3MBTL1 | |
| SCHEMBL7593231 | 0.76 | PLCG1 (0.42) | ELANERAB9APLCG1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | claimed |
| EP-0587436-A1 | Process for preparing carbapenem and penem compounds and new compounds involved in that process | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | claimed |
| US-5719275-A | REACTING SILYL ENOL ETHER WITH AZETIDINONE DERIVATIVE TO FORM INTERMEDIATE FOR PENICILLIN-TYPE ANTIBIOTIC | SANKYO COMPANY, LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |
| US-5681951-A | REACTING PENICILLIN DERIVATIVE HAVING SULFINYL OR SULFONYL GROUP IN 2 POSITION WITH SUBSTITUTED MERCAPTAN IN PRESENCE OF SALT OF GROUP IIA OR IIIA ELEMENT | SANKYO COMPANY, LIMITED (JP) | 1997-10-28 | — | — | US | disclosed |
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| US-5541317-A | PENICILLIN DERIVATIVES, CYCLIZATION OF ESTERS OR THIOESTERS | SANKYO COMPANY, LIMITED (JP) | 1996-07-30 | — | — | US | disclosed |