Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698030 | 0.87 | ELANE (0.38) | RAB9APLCG1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8038835 | 0.84 | L3MBTL1 (0.36) | RAB9APLCG1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14875145 | 0.76 | PLCG1 (0.42) | RAB9APLCG1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9198910 | 0.74 | PLCG1 (0.42) | RAB9APLCG1L3MBTL1ALDH1A1FOLH1 | |
| SCHEMBL8040724 | 0.73 | PLCG1 (0.38) | RAB9APLCG1SMN1; SMN2ELANECCR5 | |
| SCHEMBL7146947 | 0.72 | PLCG1 (0.39) | RAB9APLCG1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14875202 | 0.72 | MAOB (0.43) | RAB9APLCG1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL14875135 | 0.71 | MAOB (0.42) | RAB9APLCG1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8042511 | 0.71 | DPP8 (0.36) | RAB9APLCG1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL8695464 | 0.71 | KEAP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0587436-B1 | Process for preparing carbapenem and penem compounds and new compounds involved in that process | SANKYO CO (JP) | 2000-05-10 | — | — | EP | disclosed |
| EP-0587436-A1 | Process for preparing carbapenem and penem compounds and new compounds involved in that process | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |