Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 2/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6260237 | 0.76 | PTGER1 (0.62) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| Tibenzate SCHEMBL2110094 | 0.75 | IDO1 (0.52) | KMT2ALMNATDP1L3MBTL1SMN1; SMN2 | |
| Bicarbonate SCHEMBL27963003 | 0.74 | HTR1A (0.61) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL31757965 | 0.74 | CFD (0.68) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL1007508 | 0.74 | CFD (0.68) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL8698068 | 0.74 | HTR1A (0.53) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL6258686 | 0.74 | PTGER1 (0.50) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL3477609 | 0.73 | HTR1A (0.59) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL3980718 | 0.73 | HTR1A (0.59) | PTGER1PTGER4PTGER3PTGER2HTR1A | |
| SCHEMBL1412911 | 0.73 | HTR1A (0.59) | PTGER1PTGER4PTGER3PTGER2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834468-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, ANALGESICS TREATING RHEUMATIC DISEASE, BONE DISORDER, INJURIES | ZENECA LIMITED (GB) | 1998-11-10 | — | — | US | disclosed |