Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1042563 | 0.79 | MAPT (0.56) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL7931002 | 0.77 | ALDH1A1 (0.50) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL25425757 | 0.75 | TAAR1 (0.45) | MAPTRAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL15973333 | 0.74 | PDE2A (0.43) | RAB9ANPC1KMT2AAMY1APDE2A | |
| SCHEMBL16319094 | 0.74 | PDE2A (0.48) | RAB9ANPC1AMY1APDE2APDE10A | |
| SCHEMBL30629141 | 0.72 | NPC1 (0.50) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL321710 | 0.72 | NPC1 (0.50) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL16290879 | 0.72 | PTGS2 (0.47) | MAPTHSP90AA1HSP90AB1APPHPGD | |
| SCHEMBL25359303 | 0.71 | HSP90AA1 (0.46) | MAPTRAB9AMEN1KMT2AAMY1A | |
| SCHEMBL276095 | 0.71 | CYP1A2 (0.46) | MAPTRAB9ANPC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998011070-A1 | PROCESS FOR THE MANUFACTURE OF (2'-FLUOROPHENYL)-3-HALOPYRIDINES | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-19 | — | — | WO | disclosed |