Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379484 | 0.86 | PPARG (0.54) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL3379479 | 0.86 | PPARG (0.54) | ALDH1A1MAPTHPGDLMNASMN1; SMN2 | |
| SCHEMBL3378444 | 0.84 | NPC1 (0.54) | ALDH1A1MAPTHPGDTDP1LMNA | |
| SCHEMBL3378447 | 0.84 | NPC1 (0.54) | ALDH1A1MAPTHPGDTDP1LMNA | |
| SCHEMBL4683206 | 0.82 | MAPT (0.52) | ALDH1A1MAPTHPGDTDP1LMNA | |
| SCHEMBL6984561 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTHTTHPGDTDP1 | |
| SCHEMBL8854027 | 0.79 | TSHR (0.45) | ALDH1A1MAPTHPGDTDP1LMNA | |
| SCHEMBL203326 | 0.79 | ATM (0.60) | ALDH1A1MAPTLMNAKMT2AATM | |
| SCHEMBL193009 | 0.79 | ATM (0.60) | ALDH1A1MAPTLMNAKMT2AATM | |
| SCHEMBL194384 | 0.79 | ATM (0.60) | ALDH1A1MAPTLMNAKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804595-A | ANTIINFLAMMATORY AGENT TO TREAT PAIN CAUSED BY RHEUMATOID ARTHRITIS AND LAPAROSCOPIC SURGERY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1998-09-08 | — | — | US | disclosed |