Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034854 | 0.89 | DNM1 (0.35) | CTSK | |
| SCHEMBL3040375 | 0.88 | TRPM8 (0.30) | — | |
| SCHEMBL8697461 | 0.85 | MAPT (0.38) | — | |
| SCHEMBL3034650 | 0.85 | CTSK (0.36) | CTSK | |
| SCHEMBL3037264 | 0.84 | CTSK (0.41) | CTSK | |
| SCHEMBL7564444 | 0.84 | — | — | |
| SCHEMBL9777154 | 0.83 | MAPT (0.39) | — | |
| SCHEMBL4138235 | 0.81 | TSHR (0.37) | CTSK | |
| SCHEMBL8371036 | 0.81 | MAPT (0.42) | — | |
| SCHEMBL22342663 | 0.81 | MAPT (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5834460-A | FOR TREATMENT OF BRAIN OR PSYCHOLOGICAL DISORDERS, ALZHEIMER*S DISEASE, MENTAL RETARDATION OR AUTISM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-10 | — | — | US | disclosed |
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| US-5453514-A | Diabetes | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-09-26 | — | — | US | disclosed |