Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 10/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8464400 | 0.88 | PTGS2 (0.35) | MCL1 | |
| SCHEMBL8461149 | 0.86 | AR (0.33) | MCL1KIF11 | |
| SCHEMBL8466109 | 0.85 | MCL1 (0.32) | MCL1 | |
| SCHEMBL6049436 | 0.82 | SCN9A (0.42) | — | |
| SCHEMBL8466103 | 0.76 | MCL1 (0.36) | MCL1ALDH1A1 | |
| SCHEMBL6049378 | 0.76 | SCN9A (0.35) | ALDH1A1 | |
| SCHEMBL6049395 | 0.75 | SCN9A (0.34) | ALDH1A1 | |
| SCHEMBL8464833 | 0.74 | MCL1 (0.35) | MCL1 | |
| SCHEMBL6049387 | 0.74 | SCN9A (0.33) | ALDH1A1 | |
| SCHEMBL8464575 | 0.74 | MCL1 (0.35) | MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998028280-A1 | CERTAIN 3-[2,4-DISUBSTITUTED-5-(SUBSTITUTED AMINO)PHENYL]-1-SUBSTITUTED-6-TRIFLUOROMETHYL-2,4-(1H,3H)-PYRIMIDINEDIONE DERIVATIVES AS HERBICIDES | FMC CORPORATION (US) | 1998-07-02 | — | — | WO | disclosed |