Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 11/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8461149 | 0.89 | AR (0.33) | MCL1NPC1KMT2A | |
| SCHEMBL8698404 | 0.88 | MCL1 (0.32) | MCL1 | |
| SCHEMBL8466109 | 0.88 | MCL1 (0.32) | MCL1 | |
| SCHEMBL8466103 | 0.88 | MCL1 (0.36) | PTGS2MCL1PPOXFPR2GRIN1 | |
| SCHEMBL8462175 | 0.81 | PPOX (0.39) | PPOX | |
| SCHEMBL7901403 | 0.80 | MCL1 (0.41) | PTGS2MCL1PPOXFPR2DRD2 | |
| SCHEMBL8464833 | 0.77 | MCL1 (0.35) | MCL1DRD2TP53TSHR | |
| SCHEMBL8464575 | 0.76 | MCL1 (0.35) | MCL1TP53TSHR | |
| SCHEMBL6049436 | 0.74 | SCN9A (0.42) | — | |
| SCHEMBL8106093 | 0.74 | NOTUM (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990044-A | Selective herbicides based on aryl uracils | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |