Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | HPN | P05981 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10710980 | 0.85 | HPN (0.50) | PTGS1PTGS2HPNMAPTALOX15 | |
| SCHEMBL10708262 | 0.84 | MAPT (0.57) | PTGS1HPNMAPTALOX15SIRT5 | |
| SCHEMBL11412940 | 0.77 | SMN1; SMN2 (0.52) | PTGS1PTGS2HPNMAPTALOX15 | |
| SCHEMBL10698130 | 0.75 | ALOX15 (0.63) | PTGS1HPNMAPTALOX15SIRT5 | |
| SCHEMBL10503818 | 0.75 | ALOX15 (0.63) | PTGS1HPNMAPTALOX15SIRT5 | |
| SCHEMBL30709668 | 0.75 | CA2 (0.53) | PTGS1PTGS2HPNMAPTALOX15 | |
| SCHEMBL8768745 | 0.74 | ALOX15 (0.49) | PTGS1PTGS2HPNMAPTALOX15 | |
| SCHEMBL9504462 | 0.73 | ALOX15 (0.61) | PTGS1HPNMAPTALOX15SIRT5 | |
| SCHEMBL646923 | 0.73 | ALOX15 (0.61) | PTGS1HPNMAPTALOX15SIRT5 | |
| SCHEMBL11605148 | 0.71 | ALOX15 (0.49) | PTGS1PTGS2HPNMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0482071-B1 | NEW ANTIVIRAL AGENTS | BIODOR US HOLDING CORP (US) | 1998-01-07 | — | — | EP | claimed |
| EP-0482071-A4 | NEW ANTIVIRAL AGENTS | — | 1993-03-17 | — | — | EP | claimed |
| EP-0482071-A1 | NEW ANTIVIRAL AGENTS | BIODOR U.S. HOLDING CORPORATION (US) | 1992-04-29 | — | — | EP | claimed |
| WO-1991001124-A1 | NEW ANTIVIRAL AGENTS | BIODOR U.S. HOLDING (US) | 1991-02-07 | — | — | WO | claimed |