Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7446605 | 0.80 | KDM4E (0.57) | ALDH1A1KDM4ELTA4HKMT2AHTR1A | |
| SCHEMBL8695545 | 0.79 | HTR6 (0.45) | — | |
| SCHEMBL28311407 | 0.74 | TSHR (0.72) | ALDH1A1KDM4ELTA4HTDP1KMT2A | |
| SCHEMBL211606 | 0.73 | LTA4H (0.77) | ALDH1A1KDM4ELTA4HTDP1KMT2A | |
| SCHEMBL9122265 | 0.73 | LTA4H (0.77) | ALDH1A1KDM4ELTA4HTDP1KMT2A | |
| SCHEMBL7446659 | 0.73 | F2 (0.59) | ALDH1A1KDM4EHTR1AHTR7 | |
| SCHEMBL8696239 | 0.73 | IKBKB (0.43) | KMT2A | |
| SCHEMBL32689500 | 0.70 | KDM4E (0.50) | ALDH1A1KDM4ETDP1KMT2ASIGMAR1 | |
| SCHEMBL1374528 | 0.69 | TDP1 (0.63) | ALDH1A1KDM4ELTA4HTDP1KMT2A | |
| SCHEMBL28311408 | 0.69 | KDM4E (0.75) | ALDH1A1KDM4ELTA4HTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |