Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 5/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696239 | 0.87 | IKBKB (0.43) | HTR6F2SLC6A2SLC6A4KCNH2 | |
| SCHEMBL8695784 | 0.86 | HTR6 (0.52) | HTR6F2SLC6A2SLC6A4HTR3A | |
| SCHEMBL7451365 | 0.80 | F2 (0.67) | HTR6F2SLC6A2SLC6A4HTR3A | |
| SCHEMBL8699006 | 0.79 | ALDH1A1 (0.52) | — | |
| SCHEMBL6553101 | 0.75 | F2 (0.49) | HTR6F2SLC6A2SLC6A4HTR3A | |
| SCHEMBL7451123 | 0.74 | F2 (0.47) | HTR6F2SLC6A2SLC6A4HTR3A | |
| Hydrochloric Acid SCHEMBL6553096 | 0.74 | F2 (0.48) | HTR6F2SLC6A2SLC6A4HTR3A | |
| SCHEMBL6553019 | 0.73 | F2 (0.73) | F2CTRC | |
| SCHEMBL22265724 | 0.72 | SLC6A2 (0.53) | SLC6A2SLC6A4HTR3AKCNH2KHK | |
| SCHEMBL7451490 | 0.71 | F2 (0.70) | HTR6F2CTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |