Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8040777 | 1.00 | ESR1 (0.31) | ESR1PTGS1PDE4AKEAP1HCRTR1 | |
| SCHEMBL8040731 | 0.92 | ELANE (0.32) | — | |
| SCHEMBL8695696 | 0.88 | ESR1 (0.40) | ESR1PTGS1PDE4AKEAP1HCRTR1 | |
| SCHEMBL8039652 | 0.88 | ESR1 (0.40) | ESR1PTGS1PDE4AKEAP1HCRTR1 | |
| SCHEMBL8694071 | 0.88 | ESR1 (0.40) | ESR1PTGS1PDE4AKEAP1HCRTR1 | |
| SCHEMBL8039578 | 0.84 | L3MBTL1 (0.36) | — | |
| SCHEMBL8695468 | 0.80 | ESR1 (0.33) | ESR1PTGS1PDE4AKEAP1HCRTR1 | |
| SCHEMBL8039549 | 0.80 | ESR1 (0.33) | ESR1PTGS1PDE4AKEAP1HCRTR1 | |
| SCHEMBL8695354 | 0.78 | — | — | |
| SCHEMBL8834929 | 0.76 | SMN1; SMN2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719275-A | REACTING SILYL ENOL ETHER WITH AZETIDINONE DERIVATIVE TO FORM INTERMEDIATE FOR PENICILLIN-TYPE ANTIBIOTIC | SANKYO COMPANY, LIMITED (JP) | 1998-02-17 | — | — | US | disclosed |