Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8042493 | 1.00 | SMN1; SMN2 (0.31) | SMN1; SMN2NPC1GLAELANEHTT | |
| SCHEMBL8040731 | 0.85 | ELANE (0.32) | ELANE | |
| SCHEMBL8976102 | 0.83 | ELANE (0.32) | ELANE | |
| SCHEMBL8039606 | 0.83 | ELANE (0.32) | ELANE | |
| SCHEMBL8042490 | 0.82 | HTT (0.38) | SMN1; SMN2GLAHTTALDH1A1 | |
| SCHEMBL9429357 | 0.78 | ELANE (0.35) | ELANE | |
| SCHEMBL9427926 | 0.78 | — | — | |
| SCHEMBL8045998 | 0.77 | DPP8 (0.37) | SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL8040777 | 0.76 | ESR1 (0.31) | — | |
| SCHEMBL8699086 | 0.76 | ESR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614624-A | THIO SUBSTITUTED, ANTIBIOTICS, CHEMICAL INTERMEDIATES | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |