Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725253 | 0.82 | ALDH1A1 (0.49) | ALDH1A1GAASMN1; SMN2TDP1KDM4E | |
| SCHEMBL3105408 | 0.80 | RAB9A (0.60) | HTTSMN1; SMN2KMT2AP2RY1POLB | |
| SCHEMBL896116 | 0.79 | NPC1 (0.54) | ALDH1A1GAATDP1KMT2AKDM4E | |
| SCHEMBL896310 | 0.79 | SMN1; SMN2 (0.57) | ALDH1A1GAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL17372671 | 0.79 | MAPT (0.53) | ALDH1A1GAAHTTSMN1; SMN2TDP1 | |
| SCHEMBL50243 | 0.79 | MEN1 (0.55) | ALDH1A1GAASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL1723318 | 0.78 | METAP1 (0.54) | ALDH1A1P2RY1 | |
| SCHEMBL30283184 | 0.78 | METAP1 (0.54) | ALDH1A1P2RY1 | |
| SCHEMBL11176848 | 0.77 | KMT2A (0.72) | ALDH1A1GAAHTTSMN1; SMN2KMT2A | |
| SCHEMBL2398063 | 0.77 | KDR (0.63) | ALDH1A1HTTSMN1; SMN2TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |