Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696858 | 0.94 | TBXAS1 (0.55) | TBXAS1ALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8542041 | 0.82 | CYP19A1 (0.45) | TBXAS1CYP19A1 | |
| SCHEMBL8696336 | 0.82 | HMOX1 (0.47) | TBXAS1KMT2AMEN1CYP19A1 | |
| Hydrochloric Acid SCHEMBL8698587 | 0.81 | TBXAS1 (0.46) | TBXAS1CYP19A1 | |
| SCHEMBL8698471 | 0.81 | HMOX1 (0.46) | TBXAS1CYP19A1 | |
| SCHEMBL8542320 | 0.80 | TBXAS1 (0.62) | TBXAS1ADRA1DADRA1AADRA1B | |
| SCHEMBL6949512 | 0.80 | TBXAS1 (0.89) | TBXAS1CYP19A1 | |
| SCHEMBL7752363 | 0.79 | S1PR1 (0.49) | ALDH1A1KMT2AHCRTR1HCRTR2ADRA1D | |
| Hydrochloric Acid SCHEMBL11259498 | 0.78 | TBXAS1 (0.86) | TBXAS1CYP19A1 | |
| SCHEMBL8699130 | 0.77 | TBXAS1 (0.47) | TBXAS1ALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741800-A | ANTIINFLAMMATORY AGENT, ANTIALLERGENS | KNOLL AKTIENGESELLACHAFT (DE) | 1998-04-21 | — | — | US | disclosed |