Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695105 | 0.91 | GPR119 (0.47) | STSTGFBR1GPR119MEN1KMT2A | |
| SCHEMBL8695254 | 0.89 | MEN1 (0.45) | STSTGFBR1GPR119MEN1KMT2A | |
| SCHEMBL8702747 | 0.88 | STS (0.54) | STSF2TGFBR1GPR119MEN1 | |
| Acetic Acid SCHEMBL8698677 | 0.85 | F2 (0.57) | F2L3MBTL1CACNA1BCYP3A4RBP4 | |
| SCHEMBL8701099 | 0.85 | F2 (0.45) | STSF2TGFBR1GPR119MEN1 | |
| SCHEMBL8701363 | 0.82 | HTR6 (0.45) | STSF2TGFBR1JAK2JAK3 | |
| SCHEMBL8695575 | 0.82 | STS (0.46) | STSF2GPR119MEN1KMT2A | |
| SCHEMBL8696210 | 0.81 | STS (0.45) | STSF2MEN1KMT2APOLB | |
| SCHEMBL7443092 | 0.76 | F2 (0.76) | STSF2TGFBR1 | |
| SCHEMBL23705837 | 0.75 | JAK2 (0.53) | STSTGFBR1JAK2JAK3PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |