Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SFRP1 | Q8N474 | 4/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696210 | 0.88 | STS (0.45) | F2MEN1KMT2ASTSEPHX2 | |
| SCHEMBL8695254 | 0.87 | MEN1 (0.45) | MEN1KMT2ASTSGPR119SCN9A | |
| SCHEMBL8701363 | 0.86 | HTR6 (0.45) | F2MEN1KMT2ASTSGPR119 | |
| Acetic Acid SCHEMBL8696214 | 0.86 | F2 (0.57) | F2RBP4 | |
| SCHEMBL8699155 | 0.85 | STS (0.45) | F2MEN1KMT2ASTSRBP4 | |
| SCHEMBL8695575 | 0.85 | STS (0.46) | F2MEN1KMT2ASTSEPHX2 | |
| SCHEMBL8695105 | 0.83 | GPR119 (0.47) | MEN1KMT2ASTSGPR119TGFBR1 | |
| SCHEMBL8702747 | 0.81 | STS (0.54) | F2MEN1KMT2ASTSGPR119 | |
| SCHEMBL8700362 | 0.80 | F2 (0.46) | F2MEN1KMT2ASTSLMNA | |
| SCHEMBL8695530 | 0.78 | F2 (0.46) | F2MEN1KMT2ASTSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792769-A | POTENT ANTICOAGULANT, ANTIINFLAMMATORY AGENT; TREATMENT/PROPHYLAXIS OF RESPIRATORY SYSTEM DISORDERS, VASCULAR SYSTEM DISORDERS, ANTITUMOR AGENTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 1998-08-11 | — | — | US | disclosed |