Euscaphic Acid

Euscaphic Acid

SCHEMBL869924

C[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC(O)[C@H](O)C(C)(C)C5CC[C@]43C)[C@@H]2[C@]1(C)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 2/20 1.00
ACHE P22303 1/20 0.83
HSD11B1 P28845 3/20 0.81
PTPN1 P18031 9/20 0.78
PYGM P11217 2/20 0.73
PTPN2 P17706 2/20 0.73
GPBAR1 Q8TDU6 2/20 0.73
POLB P06746 1/20 0.73
PTPN6 P29350 1/20 0.73
HTT P42858 1/20 0.73
USP7 Q93009 1/20 0.73
AKR1B10 O60218 2/20 0.71
AKR1B1 P15121 2/20 0.71
GABRP O00591 1/20 0.61
GABRD O14764 1/20 0.61
GABRA1 P14867 1/20 0.61
GABRB1 P18505 1/20 0.61
GABRG2 P18507 1/20 0.61
GABRB3 P28472 1/20 0.61
GABRA5 P31644 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Euscaphic Acid SCHEMBL7349271 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL29228689 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL17584886 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Tomentic Acid SCHEMBL94231 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL126037 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL869457 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL13629633 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL5971379 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL7349266 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL5799713 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102573865-B Composition for preventing and treating erythrocyte aggregation 基因雷克斯制药有限公司 2016-08-24 CN claimed
CN-102740870-B Application of organic extract of Japanese roadside green in preparing medicine for treating or preventing hypertension 基因雷克斯制药有限公司 2016-06-29 CN claimed
CN-102497873-B Compositions and methods for increasing life and health GENEREX PHARMACEUTICALS, INC. (CN) 2016-04-13 CN claimed
CN-102548571-B Compositions and methods for preventing and treating brain diseases and conditions GENEREX PHARM INC 2014-08-27 CN claimed
EP-1569668-B1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF LEAD BILLION LTD (CN) 2011-07-20 EP claimed
EP-1569668-A4 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF UNIV HONG KONG CHINESE (HK) 2009-07-01 EP claimed
US-7387801-B2 Organic extract of Geum japonicum Thunb variant and use thereof THE CHINESE UNIVERSITY OF HONG KONG (CN) 2008-06-17 US claimed
US-20060134229-A1 Organic extract of geum japonicum thunb variant and use thereof CHINESE UNIVERSITY OF HONG KONG (CN) 2006-06-22 US claimed
EP-1569668-A1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (HK) 2005-09-07 EP claimed
WO-2004052381-A1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2004-06-24 WO claimed
US-9950019-B2 Compositions and methods for the prevention and treatment of brain diseases and conditions GENEREX PHARMACEUTICALS, INC. (KY) 2018-04-24 US disclosed
US-20180055896-A1 COMPOSITIONS AND METHODS FOR INCREASING LIFESPAN AND HEALTH SPAN GENEREX PHARM INC (KY) 2018-03-01 US disclosed
US-9629884-B2 Compositions and methods for increasing lifespan and health span GENEREX PHARMACEUTICALS, INC. (KY) 2017-04-25 US disclosed
CN-102573865-B Composition for preventing and treating erythrocyte aggregation 基因雷克斯制药有限公司 2016-08-24 CN disclosed
CN-102497873-B Compositions and methods for increasing life and health GENEREX PHARMACEUTICALS, INC. (CN) 2016-04-13 CN disclosed
US-20050064048-A1 Compositions comprising organic extracts of geum japonicum thunb var. and the use thereof LEAD BILLION LIMITED (HK) 2005-03-24 US disclosed
EP-1446134-A1 COMPOSITIONS COMPRISING ORGANIC EXTRACTS OF GEUM JAPONICUM THUNB VAR. AND THE USE THEREOF The Chinese University of Hong Kong (CN) 2004-08-18 EP disclosed
WO-2004052381-A1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2004-06-24 WO disclosed
WO-2003043645-A1 COMPOSITIONS COMPRISING ORGANIC EXTRACTS OF GEUM JAPONICUM THUNB VAR. AND THE USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2003-05-30 WO disclosed
US-5916919-A TRITERPENES DALHOUSIE UNIVERSITY (CA) 1999-06-29 US disclosed