Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 2/20 | 1.00 |
| ▸ | ACHE | P22303 | 1/20 | 0.83 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.81 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.78 |
| ▸ | PYGM | P11217 | 2/20 | 0.73 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.73 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.73 |
| ▸ | HTT | P42858 | 1/20 | 0.73 |
| ▸ | USP7 | Q93009 | 1/20 | 0.73 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.71 |
| ▸ | GABRP | O00591 | 1/20 | 0.61 |
| ▸ | GABRD | O14764 | 1/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.61 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.61 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.61 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.61 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Euscaphic Acid SCHEMBL7349271 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Euscaphic Acid SCHEMBL29228689 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Euscaphic Acid SCHEMBL17584886 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Tomentic Acid SCHEMBL94231 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Euscaphic Acid SCHEMBL869457 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Euscaphic Acid SCHEMBL13629633 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Euscaphic Acid SCHEMBL5971379 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Euscaphic Acid SCHEMBL7349266 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Euscaphic Acid SCHEMBL5799713 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM | |
| Euscaphic Acid SCHEMBL869924 | 1.00 | SENP1 (1.00) | SENP1ACHEHSD11B1PTPN1PYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129240-A1 | COMPOSITIONS AND METHODS FOR TASTE MODULATION | GIVAUDAN SA (CH) | 2022-06-23 | — | — | WO | disclosed |
| EP-2571354-B1 | Ursolic acid for inhibiting muscle atrophy | UNIV IOWA RES FOUND (US) | 2020-07-08 | — | — | EP | disclosed |
| US-20180118657-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2018-05-03 | — | — | US | disclosed |
| US-20160058797-A1 | PHARMACEUTICAL COMPOSITION AND METHOD FOR REGENERATING MYOFIBERS IN THE TREATMENT OF MUSCLE INJURIES | LEAD BILLION LIMITED (CN) | 2016-03-03 | — | — | US | disclosed |
| US-20160058797-A1 | PHARMACEUTICAL COMPOSITION AND METHOD FOR REGENERATING MYOFIBERS IN THE TREATMENT OF MUSCLE INJURIES | LEAD BILLION LIMITED (CN) | 2016-03-03 | — | — | US | disclosed |
| US-20140371188-A1 | COMPOSITIONS AND METHODS FOR INHIBITING MUSCLE ATROPHY AND INDUCING MUSCLE HYPERTROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2014-12-18 | — | — | US | disclosed |
| US-8853271-B2 | Method for inhibiting activity and/or expression of matrix metalloproteinase, inhibiting phosphorylation of mitogen-activated protein kinase, and/or promoting expression of collagen using tormentic acid | CHINA MEDICAL UNIVERSITY (TW) | 2014-10-07 | — | — | US | disclosed |
| US-8853271-B2 | Method for inhibiting activity and/or expression of matrix metalloproteinase, inhibiting phosphorylation of mitogen-activated protein kinase, and/or promoting expression of collagen using tormentic acid | CHINA MEDICAL UNIVERSITY (TW) | 2014-10-07 | — | — | US | disclosed |
| US-20130203712-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2013-08-08 | — | — | US | disclosed |
| EP-2425832-A1 | Tormentic acid for the treatment of skin disorders | China Medical University (TW) | 2012-03-07 | — | — | EP | disclosed |
| WO-2011146768-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2011-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371188-A1 | COMPOSITIONS AND METHODS FOR INHIBITING MUSCLE ATROPHY AND INDUCING MUSCLE HYPERTROPHY | CDKN1A, MUSK, MSTN | SENP1 528/4885ACHE 3506/4885HSD11B1 119/4885 |
| US-20160058797-A1 | PHARMACEUTICAL COMPOSITION AND METHOD FOR REGENERATING MYOFIBERS IN THE TREATMENT OF MUSCLE INJURIES | TNNC1, TNNI3, TNNT2 | SENP1 2537/4885ACHE 316/4885HSD11B1 987/4885 |
| US-20180118657-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | TNNC1, PYGM, GYS1 | SENP1 264/4885ACHE 1615/4885HSD11B1 130/4885 |
| US-20130203712-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | TNNC1, PYGM, GYS1 | SENP1 264/4885ACHE 1615/4885HSD11B1 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.