Tomentic Acid

Tomentic Acid

SCHEMBL94231

C[C@@H]1CC[C@]2(C(=O)O)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)[C@@H]5CC[C@]43C)[C@@H]2[C@]1(C)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SENP1 Q9P0U3 2/20 1.00
ACHE P22303 1/20 0.83
HSD11B1 P28845 3/20 0.81
PTPN1 P18031 9/20 0.78
PYGM P11217 2/20 0.73
PTPN2 P17706 2/20 0.73
GPBAR1 Q8TDU6 2/20 0.73
POLB P06746 1/20 0.73
PTPN6 P29350 1/20 0.73
HTT P42858 1/20 0.73
USP7 Q93009 1/20 0.73
AKR1B10 O60218 2/20 0.71
AKR1B1 P15121 2/20 0.71
GABRP O00591 1/20 0.61
GABRD O14764 1/20 0.61
GABRA1 P14867 1/20 0.61
GABRB1 P18505 1/20 0.61
GABRG2 P18507 1/20 0.61
GABRB3 P28472 1/20 0.61
GABRA5 P31644 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Euscaphic Acid SCHEMBL7349271 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL29228689 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL17584886 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL126037 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL869457 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL13629633 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL5971379 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL7349266 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL5799713 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM
Euscaphic Acid SCHEMBL869924 1.00 SENP1 (1.00) SENP1ACHEHSD11B1PTPN1PYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12605351-B2 Method for producing a composition comprising a 3-O-p-coumaroyl ester of tormentic acid from a plant cell culture, applications thereof as antiparasitic agent for the treatment of trypanosomiasis LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LU) 2026-04-21 US claimed
US-12514892-B1 Scar revisions using topical Hamelia patens extract BERRY DON WAYNE (US) 2026-01-06 US claimed
US-20250339399-A1 SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM BEIJING CREATRON INSTITUTE OF PHARMACEUTICAL RES CO LTD (CN) 2025-11-06 US claimed
EP-4630026-A1 COMPOSITIONS COMPRISING SANGUISORBA OFFICINALIS ROOT EXTRACT AND USES THEREOF CLARIANT INTERNATIONAL LTD (CH) 2025-10-15 EP claimed
CN-120202013-A Composition containing sanguisorba officinalis root extract and application thereof 科莱恩国际有限公司 2025-06-24 CN claimed
CN-119367374-A Potentilla acid compound as CB2 receptor agonist, medicament and application 赣江中药创新中心 2025-01-28 CN claimed
CN-119302965-A Application of tormentic acid in preparation of products for preventing and treating hypertension 福建中医药大学 2025-01-14 CN claimed
CN-118660707-A Supermolecule self-assembly system 北京睿创康泰医药研究院有限公司 2024-09-17 CN claimed
WO-2024120853-A1 COMPOSITIONS COMPRISING SANGUISORBA OFFICINALIS ROOT EXTRACT AND USES THEREOF CLARIANT INTERNATIONAL LTD (CH) 2024-06-13 WO claimed
CN-118047822-A Compound extracted from elm bark, and preparation method and application thereof 延边大学 2024-05-17 CN claimed
WO-2006064583-A1 TERPENE, METHOD FOR DETERMINING ITS BLOOD CONCENTRATION, AND METHOD FOR ANALYZING ITS PHARMACOKINETICS USE-TECHNO CORPORATION (JP) 2006-06-22 WO claimed
WO-2006054370-A1 GLUCONEOGENESIS INHIBITING AGENT USE-TECHNO CORPORATION (JP) 2006-05-26 WO claimed
WO-2006019881-A2 COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS AND BACTERIAL INFECTIONS ELDRIDGE GARY R (US) 2006-02-23 WO claimed
WO-2006010147-A2 CONTROL OF BIOFILM FORMATION ELDRIDGE GARY R (US) 2006-01-26 WO claimed
US-20050267055-A1 Agent for improvement of glucose tolerance USE-TECHNO CORPORATION 2005-12-01 US claimed
US-20050255569-A1 Method for producing triterpene composition USE-TECHNO CORPORATION 2005-11-17 US claimed
EP-1569668-A1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (HK) 2005-09-07 EP claimed
WO-2004052381-A1 AN ORGANIC EXTRACT OF GEUM JAPONICUM THUMB VARIANT AND USE THEREOF THE CHINESE UNIVERSITY OF HONG KONG (CN) 2004-06-24 WO claimed
EP-1355642-A2 INHIBITION OF NF-(k)B BY TRITERPENE COMPOSITIONS RESEARCH DEVELOPMENT FOUNDATION (US) 2003-10-29 EP claimed
WO-2002055016-A2 INHIBITION OF NF-λB BY TRITERPENE COMPOSITIONS RES DEV FOUNDATION (US) 2002-07-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250339399-A1 SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM S100A8, TP53, AQP1 SENP1 2358/4885ACHE 544/4885HSD11B1 810/4885
US-12605351-B2 Method for producing a composition comprising a 3-O-p-coumaroyl ester of tormentic acid from a plant cell culture, applications thereof as antiparasitic agent for the treatment of trypanosomiasis NFATC1, CYP51A1, ME1 SENP1 1598/4885ACHE 2221/4885HSD11B1 261/4885
US-20050267055-A1 Agent for improvement of glucose tolerance GPR119, GYS2, GCKR SENP1 2872/4885ACHE 3845/4885HSD11B1 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.