Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | APOB | P04114 | 1/20 | 0.33 |
| ▸ | MTTP | P55157 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703452 | 0.75 | CA1 (0.56) | CA1CA2CA12CA7CA14 | |
| SCHEMBL8668643 | 0.75 | CA1 (0.50) | CA1CA2CA12CA7CA14 | |
| SCHEMBL4808483 | 0.71 | CA1 (0.61) | CA1CA2CA12CA7CA14 | |
| SCHEMBL30595322 | 0.70 | CA1 (0.55) | CA1CA2CA12CA7CA14 | |
| SCHEMBL8668810 | 0.70 | CA1 (0.51) | CA1CA2CA12CA7CA14 | |
| SCHEMBL24535066 | 0.66 | FSCN1 (0.41) | — | |
| SCHEMBL9505624 | 0.66 | CA1 (0.63) | CA1CA2CA12CA7CA14 | |
| SCHEMBL9092252 | 0.66 | CA1 (0.41) | CA1CA2CA12CA7CA14 | |
| SCHEMBL30595323 | 0.66 | MTNR1A (0.77) | CA1CA2CA12CA7CA14 | |
| SCHEMBL1029693 | 0.66 | MTNR1A (0.77) | CA1CA2CA12CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005651-A1 | NOVEL GLUTAMATE RECEPTOR ANTAGONISTS: FUSED CYCLOALKYL QUINOXALINEDIONES | WARNER-LAMBERT COMPANY (US) | 1998-02-12 | — | — | WO | disclosed |