Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 6/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8700025 | 0.99 | AOC2 (0.40) | AOC2F10PDGFRBPDGFRAFLT1 | |
| Hydrochloric Acid SCHEMBL8705820 | 0.80 | AOC2 (0.42) | AOC2F10ROCK2NSD2POLB | |
| SCHEMBL8699862 | 0.80 | AOC2 (0.42) | AOC2F10ROCK2NSD2POLB | |
| SCHEMBL7825574 | 0.80 | PDGFRB (0.52) | PDGFRBPDGFRAFLT1FLT4KDR | |
| SCHEMBL8700313 | 0.79 | AOC2 (0.43) | AOC2F10ROCK2NSD2POLB | |
| SCHEMBL7827587 | 0.79 | PDGFRB (0.38) | PDGFRBPDGFRAFLT1FLT4KDR | |
| Hydrochloric Acid SCHEMBL8701063 | 0.79 | AOC2 (0.41) | AOC2F10ROCK2NSD2POLB | |
| Hydrochloric Acid SCHEMBL8699397 | 0.78 | AOC2 (0.43) | AOC2F10ROCK2NSD2POLB | |
| Hydrochloric Acid SCHEMBL7823645 | 0.78 | PDGFRB (0.38) | PDGFRBPDGFRAFLT1FLT4KDR | |
| Hydrochloric Acid SCHEMBL8699440 | 0.77 | PLA2G10 (0.35) | AOC2F10ROCK2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |