Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | APEX1 | P27695 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8699397 | 0.99 | AOC2 (0.43) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8699862 | 0.90 | AOC2 (0.42) | AOC2F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8701063 | 0.88 | AOC2 (0.41) | AOC2F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8705820 | 0.84 | AOC2 (0.42) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8700691 | 0.82 | AOC2 (0.40) | AOC2F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8700230 | 0.81 | AOC2 (0.39) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8700634 | 0.81 | F10 (0.45) | AOC2F2F10PRSS1PRSS2 | |
| SCHEMBL8705516 | 0.80 | AOC2 (0.68) | AOC2L3MBTL1MAPTTDP1CTDSP1 | |
| SCHEMBL8699348 | 0.79 | AOC2 (0.40) | AOC2F2F10PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL8700020 | 0.79 | AOC2 (0.66) | AOC2L3MBTL1MAPTTDP1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |