Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29694978 | 0.83 | ERN1 (0.47) | ERN1ALDH1A1SMN1; SMN2LY96 | |
| SCHEMBL4631891 | 0.82 | GAA (0.42) | ALDH1A1MEN1KMT2ARXFP1TSHR | |
| SCHEMBL23122028 | 0.82 | ERN1 (0.49) | ERN1ALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL8704103 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3128179 | 0.77 | TLR2 (0.46) | ERN1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL12858446 | 0.76 | ERN1 (0.44) | ERN1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9835129 | 0.76 | CYP3A4 (0.49) | ERN1ALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL15974038 | 0.75 | ACHE (0.50) | ERN1ACHEALDH1A1MEN1KMT2A | |
| SCHEMBL13828998 | 0.75 | ERN1 (0.43) | ERN1ACHEALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8701996 | 0.74 | ALDH1A1 (0.46) | ERN1ACHEALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008837-A1 | PHENYLBUTANOL DERIVATIVES, METHODS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | FARMACON, INC. (US) | 1998-03-05 | — | — | WO | disclosed |