Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 2/20 | 0.39 |
| ▸ | DHFR | P00374 | 3/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699358 | 0.81 | IDO1 (0.39) | IDO1AGXTF2 | |
| SCHEMBL8701740 | 0.80 | IDO1 (0.38) | GGPS1IDO1AGXTF2 | |
| SCHEMBL9900879 | 0.77 | IDO1 (0.43) | IDO1AGXTF2FFAR1 | |
| SCHEMBL8703174 | 0.77 | MAPK1 (0.41) | MAPK1L3MBTL1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL8699741 | 0.76 | PPARA (0.43) | GGPS1IDO1AGXT | |
| SCHEMBL15778630 | 0.76 | IDO1 (0.60) | IDO1AGXTSMN1; SMN2DRD2 | |
| SCHEMBL8715771 | 0.76 | IDO1 (0.39) | IDO1AGXTF2 | |
| Fluoride Ion SCHEMBL31385474 | 0.75 | DHFR (0.44) | GGPS1DHFRTSHR | |
| SCHEMBL8699534 | 0.75 | PPARA (0.57) | MAPK1L3MBTL1TSHRTDP1KDM4E | |
| SCHEMBL8699363 | 0.74 | TSHR (0.38) | MAPK1TSHRIDO1AGXTF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008838-A1 | SUBSTITUTED AMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |