Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | AGXT | P21549 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715771 | 0.85 | IDO1 (0.39) | IDO1AGXTPPARAPPARGCYP4F2 | |
| SCHEMBL8699744 | 0.83 | BTN3A1 (0.36) | IDO1AGXTPPARAPPARGCYP4F2 | |
| SCHEMBL8699741 | 0.83 | PPARA (0.43) | IDO1AGXTPPARAPPARGGGPS1 | |
| SCHEMBL8698655 | 0.82 | IDO1 (0.39) | IDO1AGXTPPARAPPARGCYP4F2 | |
| SCHEMBL15778630 | 0.80 | IDO1 (0.60) | IDO1AGXTMAOB | |
| SCHEMBL8699737 | 0.80 | GGPS1 (0.39) | IDO1AGXTGGPS1F2 | |
| SCHEMBL8699358 | 0.80 | IDO1 (0.39) | IDO1AGXTCYP4F2CYP4A11MAOB | |
| SCHEMBL8702327 | 0.79 | PPARA (0.61) | PPARAPPARGCYP4F2CYP4A11MAOB | |
| SCHEMBL28079112 | 0.78 | IDO1 (0.40) | IDO1AGXTMAOBGABRA1GABRG2 | |
| SCHEMBL840465 | 0.76 | GABRA1 (0.45) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008838-A1 | SUBSTITUTED AMINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-03-05 | — | — | WO | disclosed |