Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | AGXT | P21549 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 6/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676231 | 0.86 | TAAR1 (0.35) | IDO1AGXTGABRA1GABRG2GABRB3 | |
| SCHEMBL15778630 | 0.82 | IDO1 (0.60) | IDO1AGXTMAOB | |
| SCHEMBL1241080 | 0.79 | ENPP2 (0.49) | IDO1AGXTENPP2 | |
| SCHEMBL27840926 | 0.79 | IDO1 (0.40) | IDO1AGXTMAOBGABRA1GABRG2 | |
| SCHEMBL8699358 | 0.79 | IDO1 (0.39) | IDO1AGXTMAOBF2 | |
| SCHEMBL8715771 | 0.79 | IDO1 (0.39) | IDO1AGXTMAOBGABRA1GABRG2 | |
| SCHEMBL8698655 | 0.79 | IDO1 (0.39) | IDO1AGXTMAOBGABRA1GABRG2 | |
| SCHEMBL840465 | 0.79 | GABRA1 (0.45) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL8701740 | 0.78 | IDO1 (0.38) | IDO1AGXTMAOBGABRA1GABRG2 | |
| SCHEMBL722684 | 0.77 | IDO1 (0.56) | IDO1AGXTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669553-A | Substituted benzoazepines as Toll-like receptor modulators | 文蒂雷克斯药品公司 | 2016-06-15 | — | — | CN | disclosed |