Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699370 | 0.75 | PARP1 (0.41) | HTR6TP53THRBHCRTR1KMT2A | |
| SCHEMBL8695720 | 0.72 | F2 (0.42) | PARP1 | |
| SCHEMBL8699367 | 0.69 | HTR6 (0.40) | HTR6TP53PARP1MAPTSLC16A3 | |
| SCHEMBL8699372 | 0.68 | PARP1 (0.41) | HTR6TP53THRBHCRTR1KMT2A | |
| SCHEMBL8701245 | 0.67 | TSHR (0.52) | TP53THRBHCRTR1KMT2AMAPT | |
| SCHEMBL2997901 | 0.66 | KDM4E (0.58) | HTR6PARP1MAPTSLC16A3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27862604 | 0.65 | KDM4E (0.57) | HTR6PARP1MAPTSLC16A3ALDH1A1 | |
| SCHEMBL1161161 | 0.64 | KDM4E (0.54) | HTR6KMT2APARP1MAPTSLC16A3 | |
| SCHEMBL29087055 | 0.62 | KDM4E (0.51) | HTR6PARP1MAPTSLC16A3TSHR | |
| SCHEMBL27771086 | 0.61 | MAPK1 (0.48) | HTR6TP53MAPTALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |