Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8696373 | 0.76 | KAT6A (0.48) | ALDH1A1GAALMNAHCRTR1KMT2A | |
| SCHEMBL8701236 | 0.74 | HPGD (0.55) | TSHRGFERALOX15ALDH1A1HPGD | |
| SCHEMBL9225350 | 0.71 | TSHR (0.54) | TSHRGFERALOX15ALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7298291 | 0.71 | TSHR (0.53) | TSHRGFERALOX15ALDH1A1GAA | |
| SCHEMBL7296629 | 0.69 | HPGD (0.49) | TSHRGFERALOX15ALDH1A1GAA | |
| SCHEMBL3137764 | 0.69 | TRPV1 (0.54) | TSHRALOX15ALDH1A1GAAHPGD | |
| Bicarbonate SCHEMBL15225983 | 0.69 | ALDH1A1 (0.90) | TSHRGFERALDH1A1GAAHPGD | |
| SCHEMBL5723290 | 0.68 | SMN1; SMN2 (0.50) | TSHRGFERALOX15ALDH1A1GAA | |
| SCHEMBL15225714 | 0.68 | ALDH1A1 (1.00) | TSHRGFERALOX15ALDH1A1LMNA | |
| SCHEMBL8699376 | 0.67 | HTR6 (0.43) | TSHRGFERALOX15ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |