Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8695713 | 0.73 | F2 (0.39) | SCN4A | |
| SCHEMBL8699376 | 0.69 | HTR6 (0.43) | HTR6PARP1MAPTALDH1A1GAA | |
| SCHEMBL2997901 | 0.64 | KDM4E (0.58) | HTR6PARP1MAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL27862604 | 0.63 | KDM4E (0.57) | HTR6PARP1MAPTALDH1A1GAA | |
| SCHEMBL1161161 | 0.62 | KDM4E (0.54) | HTR6PARP1MAPTGAAKDM4E | |
| SCHEMBL29087025 | 0.62 | KDM4E (0.48) | HTR6PARP1MAPTGAAKDM4E | |
| SCHEMBL7421672 | 0.61 | TMEM97 (0.39) | HTR6PARP1KDM4ESLC40A1SLC16A3 | |
| SCHEMBL8701232 | 0.61 | ALDH1A1 (0.49) | MAPTALDH1A1HTR7 | |
| SCHEMBL29087055 | 0.60 | KDM4E (0.51) | HTR6PARP1MAPTGAAKDM4E | |
| SCHEMBL22305605 | 0.58 | SCN4A (0.92) | PIK3CDSCN4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741792-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |
| US-5741799-A | ANTICOAGULANTS OF SULFONAMIDO HETEROCYCLIC THROMBIN INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-21 | — | — | US | disclosed |