Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8701324 | 0.94 | MAOA (0.56) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL14353222 | 0.94 | MAOA (0.59) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL3991531 | 0.88 | MAOA (0.59) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL27631765 | 0.87 | ELANE (0.59) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL28056451 | 0.85 | ELANE (0.58) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL8359453 | 0.84 | MEN1 (0.55) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL29257073 | 0.83 | ADORA2A (0.47) | TDP1ALDH1A1MAPK1L3MBTL1LMNA | |
| SCHEMBL8022619 | 0.82 | TDP1 (0.47) | MAOATDP1RXRA | |
| SCHEMBL16145028 | 0.80 | ALDH1A1 (0.58) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL27593593 | 0.80 | MAPK1 (0.58) | MAOAMAOBTDP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733880-A | ANTITUMOR AGENTS | NAPIER UNIVERSITY VENTURES LIMITED (GB) | 1998-03-31 | — | — | US | disclosed |