Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | HBB | P68871 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699417 | 0.94 | MAOA (0.53) | MAOAMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL3991531 | 0.90 | MAOA (0.59) | MAOAMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL14353222 | 0.90 | MAOA (0.59) | MAOAMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL8359453 | 0.86 | MEN1 (0.55) | MAOAMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL8020835 | 0.83 | TDP1 (0.45) | MAOATDP1ADORA2AFGRPIM1 | |
| SCHEMBL16145028 | 0.83 | ALDH1A1 (0.58) | MAOAMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL6682201 | 0.80 | MAPK1 (0.64) | MAOAMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL3111027 | 0.79 | MEN1 (0.62) | MAOAMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL8405647 | 0.78 | MAPT (0.47) | MAOAMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL8022619 | 0.78 | TDP1 (0.47) | MAOATDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733880-A | ANTITUMOR AGENTS | NAPIER UNIVERSITY VENTURES LIMITED (GB) | 1998-03-31 | — | — | US | disclosed |