Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.60 |
| ▸ | CTSS | P25774 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 6/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058761 | 0.90 | SMN1; SMN2 (0.50) | CTSKCTSSSMN1; SMN2CASP1PPARA | |
| SCHEMBL31360771 | 0.86 | SMN1; SMN2 (0.49) | CTSKCTSSSMN1; SMN2CASP1CTSL | |
| SCHEMBL3881683 | 0.85 | CTSS (0.65) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL8696309 | 0.85 | CTSS (0.65) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL8062883 | 0.85 | CTSS (0.65) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL6344320 | 0.85 | CTSK (0.68) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL12560624 | 0.85 | CTSK (0.68) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL7032329 | 0.85 | CTSK (0.68) | CTSKCTSSCTSLCTSBPPARA | |
| SCHEMBL13205578 | 0.84 | CASP1 (0.57) | CTSKSMN1; SMN2CASP1CTSLCTSB | |
| SCHEMBL18653898 | 0.84 | CTSK (0.64) | CTSKCTSSCTSLCTSBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726319-A | Biphenyl substituted dipeptide analogs promote release of growth hormone | MERCK & CO., INC. (US) | 1998-03-10 | — | — | US | disclosed |