Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EDNRB | P24530 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7626374 | 0.90 | MEN1 (0.40) | TSHRMEN1KMT2ALMNAGRM1 | |
| SCHEMBL8699467 | 0.86 | TSHR (0.36) | TSHRMEN1KMT2ALMNAGRM1 | |
| SCHEMBL8706000 | 0.86 | TSHR (0.44) | TSHRMEN1KMT2ALMNAGAA | |
| SCHEMBL8699760 | 0.79 | ALDH1A1 (0.39) | TSHRMEN1KMT2ALMNAGRM1 | |
| SCHEMBL8699064 | 0.78 | L3MBTL1 (0.39) | TSHRMEN1KMT2AGRM1GAA | |
| SCHEMBL8701288 | 0.77 | ALDH1A1 (0.40) | TSHRMEN1KMT2AGRM1GAA | |
| SCHEMBL7628968 | 0.76 | MEN1 (0.46) | TSHRMEN1KMT2ALMNAGAA | |
| SCHEMBL12934685 | 0.73 | C5AR1 (0.36) | LMNAGAAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9016302 | 0.72 | GRM1 (0.38) | TSHRMEN1KMT2AGRM1GAA | |
| SCHEMBL8699309 | 0.72 | TSHR (0.39) | TSHRMEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5780472-A | ANTITUMOR AGENTS | SAMJIN PHARMACEUTICAZL CO., LTD. (KR) | 1998-07-14 | — | — | US | disclosed |
| EP-0749425-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARM. CO., LTD. (KR) | 1996-12-27 | — | — | EP | disclosed |
| WO-1996021648-A1 | NEW PIPERAZINE DERIVATIVES AND METHODS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 1996-07-18 | — | — | WO | disclosed |