Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699459 | 0.75 | HTR2A (0.39) | PPARGPPARAHTR2AHRH3CA1 | |
| SCHEMBL3696413 | 0.72 | KCNA3 (0.61) | KCNA3TAAR1ALDH1A1RECQLMAPT | |
| SCHEMBL10785918 | 0.71 | KCNA3 (0.43) | KCNA3TAAR1ALDH1A1RECQLMAPT | |
| SCHEMBL5353138 | 0.71 | HTR2A (0.64) | HTR2AHRH3CA1CA2KMT2A | |
| SCHEMBL5583706 | 0.70 | KCNA3 (0.65) | KCNA3TAAR1ALDH1A1RECQL | |
| SCHEMBL6539549 | 0.70 | KCNA3 (0.73) | KCNA3TAAR1ALDH1A1RECQL | |
| SCHEMBL28467316 | 0.69 | GPR3 (0.33) | HTR2ACA1CA2 | |
| SCHEMBL833958 | 0.69 | NFE2L2 (0.51) | HRH3 | |
| SCHEMBL27608668 | 0.69 | HTR2A (0.47) | HTR2AHRH3CA1CA2KMT2A | |
| SCHEMBL7574105 | 0.69 | HTR2A (0.61) | HTR2AHRH3CA1CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |