Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | FABP7 | O15540 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238419 | 0.76 | JAK2 (0.33) | — | |
| SCHEMBL8699463 | 0.75 | PPARG (0.47) | HTR2APPARGPPARACA1CA2 | |
| SCHEMBL4778663 | 0.75 | IDO1 (0.38) | — | |
| SCHEMBL2008537 | 0.73 | KCNH2 (0.32) | — | |
| SCHEMBL2458787 | 0.73 | — | — | |
| SCHEMBL20138462 | 0.72 | MEN1 (0.43) | — | |
| SCHEMBL8217123 | 0.72 | KMT2A (0.33) | — | |
| SCHEMBL4722102 | 0.70 | GPR3 (0.32) | HTR2A | |
| SCHEMBL5353138 | 0.70 | HTR2A (0.64) | HTR2ACA1CA2TDO2HRH3 | |
| SCHEMBL348920 | 0.70 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773469-A | Diaryl antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-06-30 | — | — | US | disclosed |