Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 8/20 | 0.64 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 5/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8697927 | 0.88 | CCR2 (0.67) | CCR2PLA2G10ALDH1A1CYP1A2POLB | |
| SCHEMBL8697536 | 0.88 | CCR2 (0.58) | CCR2PLA2G10ALDH1A1CYP1A2POLB | |
| SCHEMBL8698288 | 0.85 | CCR2 (0.69) | CCR2PLA2G10PPARGSERPINE1GPR35 | |
| SCHEMBL8698044 | 0.84 | CCR2 (0.64) | CCR2PLA2G10PPARGSERPINE1 | |
| SCHEMBL5378162 | 0.80 | CCR2 (1.00) | CCR2PLA2G10ALDH1A1CYP1A2POLB | |
| SCHEMBL7076414 | 0.79 | CCR2 (0.76) | CCR2PLA2G10ALDH1A1CYP1A2POLB | |
| SCHEMBL8700231 | 0.79 | PPARG (0.62) | CCR2PPARGSERPINE1 | |
| SCHEMBL8696938 | 0.78 | CCR2 (0.66) | CCR2PLA2G10ALDH1A1CYP1A2POLB | |
| SCHEMBL8791564 | 0.78 | ADRB2 (0.49) | CCR2SERPINE1 | |
| SCHEMBL8697036 | 0.77 | CCR2 (0.60) | CCR2ALDH1A1CYP1A2POLBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767133-A | Secondary amines as antidiabetic and antiobesity agents | PFIZER INC. (US) | 1998-06-16 | — | — | US | disclosed |