Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.60 |
| ▸ | EDNRA | P25101 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | WNT3A | P56704 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7842141 | 0.91 | KMT2A (0.58) | KMT2AMAPK9EDNRACYP1A2CYP2C9 | |
| SCHEMBL13776921 | 0.83 | KMT2A (0.63) | KMT2AMAPK9RAB9ANPC1MEN1 | |
| SCHEMBL9503768 | 0.83 | L3MBTL1 (0.68) | KMT2ARAB9ANPC1MEN1L3MBTL1 | |
| SCHEMBL8695546 | 0.82 | KMT2A (0.61) | KMT2AMAPK9CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL26717284 | 0.80 | KMT2A (0.61) | KMT2AMAPK9CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8700371 | 0.80 | EDNRA (0.60) | KMT2AMAPK9EDNRARAB9ANPC1 | |
| SCHEMBL26624014 | 0.79 | KMT2A (0.72) | KMT2ARAB9ANPC1MEN1CTNNB1 | |
| SCHEMBL21656188 | 0.78 | EDNRA (0.62) | KMT2AMAPK9EDNRACYP1A2CYP2C9 | |
| SCHEMBL7830896 | 0.77 | KMT2A (0.44) | KMT2AMAPK9EDNRANPC1MEN1 | |
| SCHEMBL15979976 | 0.76 | CTNNB1 (0.78) | KMT2ARAB9ANPC1MEN1CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015524-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF BETA-KETONITRILES | WARNER-LAMBERT COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |